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Esketamine & Treatment Resistant Depression

Clinical information, referral pathways, and patient eligibility guidance for healthcare professionals referring to GoodMind.

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About Esketamine

Recognising the signs early is the first step towards getting support.

Persistent low mood
Loss of motivation
Difficulty Concentrating
Feeling Isolated or Unseen
read
Think You Recognise These Symptoms?

Our clinician-guided programs are designed to help you feel supported and understood.

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Compassionate, specialist support for treatment-resistant depression.

GoodMind was founded by clinicians and healthcare operators to make evidence-based, in-clinic treatments for TRD accessible to Australians — including DVA veterans and first responders.

Learn About Esketamine
0468 054 264

What you can expect from GoodMind

  • Clinician-led care. FRANZCP-qualified psychiatrists across all clinic sites. TGA and J&J accreditation standards.
  • Evidence-based treatment. TGA-registered. PBS-listed since May 2025. Phase 3 RCT evidence base (TRANSFORM, SUSTAIN).
  • Veteran & first responder focus. Calm, relaxing environments developed with trauma-informed care in mind.
  • Shared care model. We work with the patients primary psychiatrist, and alongside their preferred psychotherapist practitioner to provide holistic care.
  • Fast triage. All referrals reviewed within 24–48 hours. Patients typically commence treatment within two weeks.

Admistrative Information

  • Patient contact details — mobile and email
  • Medicare number
  • Preferred clinic location — Sydney CBD, Chatswood, Melbourne, Brisbane, Gold Coast, or Darwin

The best results come from the best support. Meet our professionals.

Dr David Graham

Medical Director and Psychiatrist
Dr Graham is passionate about social justice, trauma, and veteran and first responder mental health. He came to medicine following a successful career in Defence, which included two deployments to Afghanistan. This experience drew him to Psychiatry as a specialty. Dr Graham has advanced qualifications in addition to his MBBS, including a Masters of Psychiatric Medicine and a Doctor of Philosophy.

Jodie Woolf

Clinical Care Lead & Health Consultant
Originally from South Africa, Jodie is a dedicated registered nurse, nurse immuniser, health consultant, and qualified naturopathic nutritionist with extensive experience across diverse healthcare settings, including mental health. She is also an Accredited Mental Health First Aider™ (MHFAider®) through MHFA Australia. Known for her warm, approachable nature and strong communication skills, Jodie is passionate about guiding individuals through their care journeys with empathy and professionalism. She focuses on comprehensive health assessments, coordination during treatment programs, and supporting individuals throughout their experience. Jodie brings a holistic perspective that integrates clinical knowledge with lifestyle and wellbeing insights. She embodies GoodMind Therapeutics’ commitment to delivering supportive, person-centred care. Outside of work, Jodie enjoys keeping up with the latest in health and wellness.

Dr. Lauren Barker

CEO & Co-Founder
Lauren began her career as a medical doctor in New Zealand, working for several years across a range of mental health and emergency medicine settings. She transitioned into management consulting with Bain & Company in Australia, to focus on system-level impact and has since worked with leading Australian healthcare organisations to improve access, efficiency, and outcomes for patients. At GoodMind, she brings together clinical and strategic expertise to help build a more compassionate, effective system for people seeking progressive mental health care.

Anne Louise

Clinic Lead in Darwin
Anne leads the Darwin clinical team with a calm, compassionate presence and a deep commitment to patient care. With extensive experience in mental health and wellbeing, she plays a key role in guiding individuals through their treatment journey — from initial assessment to ongoing support. Her leadership style is grounded in empathy and collaboration, ensuring that every person receives care that is tailored to their needs and delivered with the highest level of clinical excellence. Anne is passionate about creating a safe, supportive environment where individuals feel heard, understood, and empowered throughout their experience. Combining clinical expertise with a holistic understanding of health and lifestyle, Anne reflects GoodMind Therapeutics’ mission to deliver thoughtful, person-centred care. Beyond the clinic, she enjoys exploring new developments in the health and wellness space.

Amanda Neal

Partnerships Manager
As the wife of a former serving member who dedicated 15 years to the Defence Force, Amanda experienced firsthand the toll military life can take – not just on those who serve, but on the families who stand beside them. Over the years, she watched husband navigate the mental and physical challenges that come with service, and experienced the ripple effects that reach far beyond the uniform. Amandaʼs mission is clear: to be a voice to ensure that every veteran, first responder, and their loved ones know they have options when it comes to their mental health.

Dr David Graham

Medical Director and Psychiatrist

Dr Jennifer Long

Psychiatrist Consultant

Dr. Amy Carmichael

Integrative Medical Practitioner & Lifestyle Medicine Specialist

Nick Pincombe

Pharmasist and Advisor

Amanda Neal

Partnerships Manager

Jodie Woolf

Clinical Care Lead & Health Consultant

Dr. Lauren Barker

CEO & Co-Founder

Gaius Tan

COO & Co-Founder

Thillak Naidu

Operations Associate

Jacqui Bulleid

Operation Manager

Anne Louise

Clinic Lead in Darwin
View Full Team

Your Questions, Answered.

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0468 054 264
What are clinician-guided programs at GoodMind?

Clinician-guided programs at GoodMind are structured esketamine therapy courses delivered in a dedicated clinical setting by AHPRA-registered psychiatrists and mental health nurses, designed for adults with treatment-resistant depression.

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Esketamine therapy at GoodMind is delivered by a clinical team led by AHPRA-registered psychiatrists, supported by mental health nurses and nurse practitioners at every clinic site.

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Esketamine therapy is safe when delivered under the strict in-clinic monitoring protocol used at GoodMind, and Spravato has one of the largest randomised evidence bases of any rapid-acting antidepressant. Intranasal esketamine has been TGA-registered for treatment-resistant depression since March 2021 and PBS-listed since May 2025.

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A full esketamine therapy course at GoodMind runs for a minimum of 8 weeks, with most patients continuing in maintenance for several months depending on their clinical response.

Find support

Yes, the Pharmaceutical Benefits Scheme (PBS) has subsidised Spravato (esketamine) for eligible adults with treatment-resistant depression since 1 May 2025, making it the first new PBS-listed medicine for major depression in more than three decades.

Find support
Request Consultation
0468 054 264

Ready to refer a patient?

Referrals reviewed within 24–48 hours. Patients typically commence treatment within two weeks.

Submit a Referral
View Referral Process

Urgent query? Call 0468 054 264 

info@goodmindteam.com.au 

Esketamine (Spravato): clinical information for healthcare professionals.

Intranasal, non-competitive NMDA receptor antagonist indicated for adults with treatment-resistant depression. TGA-registered March 2021. PBS-listed May 2025.

Refer a patient:

Submit Referral
Check Patient Eligibility

Esketamine Indications

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Check Patient Eligibility

Approved Indication

Spravato is indicated for adults with treatment-resistant depression (TRD) – Major Depressive Disorder where two or more antidepressants of adequate dose and duration have failed within the current depressive episode.

  • The patient must be able to attend in-clinic sessions for treatment monitoring.

Dosing and administration schedule

All doses are self-administered by the patient under supervision at GoodMind clinic

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Check Patient Eligibility

Induction phase: Weeks 1–4

Twice weekly dosing

Starting dose (most adults): 56 mg for doses 1 & 2, then typically 84 mg

Elderly (65+): start at 28 mg, titrate on tolerability

Maintenance phase: Week 5+

Weeks 5–8: once weekly

Week 9+: once weekly or fortnightly

Frequency individualised to clinical response

Inclusion & exclusion checklist

Eligibility critera

  • Adult with confirmed MDD diagnosis
  • Two or more adequate antidepressant trials failed
  • Physically able to attend in-person clinic sessions (2+ hours per visit)
  • No active or recent substance use disorder
  • BP within acceptable range pre-session (<140/90 mmHg general guide)

Contraindications

  • Aneurysmal vascular disease (intracranial, thoracic, abdominal aorta, peripheral arterial)
  • Arteriovenous malformation
  • History of intracerebral haemorrhage
  • Hypersensitivity to esketamine, ketamine, or any excipient
  • Active psychotic disorder (relative — individual risk-benefit)
  • Active substance use disorder within the last 12 months
  • Uncontrolled hypertension >140/90 mmHg pre-dose
Submit Referral
Check Patient Eligibility

Comorbidities — Guidance for referring clinicians

Important Information to Include in Referral

  • Anxiety disorders (GAD, panic, social anxiety, OCD) — not a contraindication. Include current treatment.
  • PTSD — not a contraindication. Highly relevant.
  • ADHD — note current stimulant use (BP monitoring implications). Not a contraindication.
  • Substance use history — active disorder within 12 months is a relative contraindication. Document historical use clearly.
  • Bipolar disorder — not a standard indication. Discuss with GoodMind clinical team before referring.

Medical comorbidities — please document

  • Hypertension — if controlled, proceed. If uncontrolled (>140/90), optimise before referring. Include antihypertensives.
  • Cardiovascular disease — individual risk-benefit assessment required. Document clearly.
  • Hepatic impairment — moderate-to-severe impairment — flag for the GoodMind psychiatrist. May affect dose titration.

How Esketamine differs from IV or subcutaneous ketamine

Spravato is the only TGA-registered, PBS-subsidised ketamine-class medicine for TRD in Australia.

Esketamine (Spravato) Racemic ketamine (IV/IM)
TGA approval Registered for TRD Not registered for TRD (off-label)
PBS subsidy Yes — from May 2025 No
Route Intranasal IV infusion or IM injection
Setting Dedicated GoodMind clinic Variable — anaesthetist-led or off-label psychiatry
Dosing schedule Standardised induction + maintenance No standardised protocol
Evidence base Phase 3 RCTs — TRANSFORM & SUSTAIN Smaller academic studies

Discuss a referral with our clinical team.

For questions about the clinical evidence or suitability of a specific
patient, call our clinical team Monday to Friday 9am–5pm AEST.

Submit a Referral
Download Clinical Summary
View Referral Process

Urgent query? Call 0468 054 264 

info@goodmindteam.com.au 

How to refer a patient to GoodMind for Esketamine therapy.

Referrals are accepted from GPs, psychiatrists, and other medical specialists. Most patients are contacted within 48 hours and commence treatment within two weeks.

Refer a patient:

Submit Referral
Check Patient Eligibility

Esketamine is a Psychiatrist Only Prescription Medication

You can referer your patient to a GoodMind psychiatrist for end to end management.

If you are a psychiatrist and wish to prescribe for your patient, we can arrange their treatment and monitoring within our clinic under your care. Please email us for more information on that process.

The Journey To Treatment

Submit Referral
Check Patient Eligibility

1

Confirm the patient meets eligibility criteria

Adults with treatment-resistant depression. Review major contraindications

2

Complete the online referral form

Approximately five minutes. The form collects the clinical information our psychiatrists need to triage promptly.

3

Clinical triage within 24–48 hours

Patient will be contact by Support Specialist and re-screened for contraindications. Full treatment process, costs and considerations outlined

4

Initial Psychiatric Assessment

Patient booked in for psychiatry review by a GoodMind psychiatrist to review eligibility for esketamine. Occurs within one to two weeks.

5

Treatment

Patient commences treatment at their nearest clinic, with regular reviews by the treating clinician

6

Ongoing Care

We actively referrer all our patients to psychotherapy to improve their outcomes. The neuroplastic effects of Esketamine are strongest within the first 24-48hrs after treatment

What to include in your referral

To avoid delays in patient contact, please include the following in the form or accompanying letter.

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0468 054 264
Clinical Information
  • Confirmed diagnosis of Major Depressive Disorder (current episode)
  • History of prior antidepressant trials — minimum two different classes, with dose, duration, and reason for cessation
  • Current medications — particularly benzodiazepines, opioids, stimulants, MAOIs, and zntihypertensives
  • Relevant medical comorbidities — cardiovascular, cerebrovascular, hepatic, respiratory
  • Any known contraindications
Admistrative Information
  • Patient contact details — mobile and email
  • Medicare number
  • Preferred clinic location — Sydney CBD, Chatswood, Melbourne, Brisbane, Gold Coast, or Darwin

Ready to refer a patient?

Referrals reviewed within 24–48 hours. Patients typically commence treatment within two weeks.

Submit a Referral
View Referral Process

Urgent query? Call 0468 054 264 

info@goodmindteam.com.au 

Veterans & First Responders

Access fully funded care for eligible patients. Emerging evidence on Esketamine efficacy for comorbid TRD and PTSD.

Refer a patient:

Submit Referral
Check Patient Eligibility

DVA patients & veterans

GoodMind has specialist experience supporting DVA patients and first responders with treatment-resistant depression, including those with complex trauma presentations.

  • DVA-covered patients — please flag DVA status on the referral form
  • GoodMind liaises directly with DVA on eligibility and coverage
  • GoodMind has a network of DVA psychologists and health providers to support holistic care
Submit Referral
Check Patient Eligibility

First responders

For many first responders, accessing mental health care can be challenging due to long wait periods, limited availability of providers, or the demands of their work schedules. GoodMind Therapeutics provides mental health related services for police officers, paramedics, and firefighters across Australia.

  • GoodMind has a network of trauma-informed psychologists and health providers to support holistic care for first-responders
  • First responders (WorkCover-covered) — flag on referral form for appropriate pathway guidance
Submit Referral
Check Patient Eligibility

Ready to refer a patient?

Referrals reviewed within 24–48 hours. Patients typically commence treatment within two weeks.

Submit a Referral
View Referral Process

Urgent query? Call 0468 054 264 

info@goodmindteam.com.au 

The largest randomised evidence base of any rapid-acting antidepressant.

Summary of the pivotal TRANSFORM and SUSTAIN trial programs, real-world evidence, and MADRS outcome data for clinical reference.

Refer a patient:

Submit Referral
Check Patient Eligibility

Summary of Clinical Evidence

Spravato is the only TGA-registered, PBS-subsidised ketamine-class medicine for TRD in Australia and carries the most robust Phase 3 RCT evidence base for any rapid-acting antidepressant currently available. The PBS listing from May 2025 reflects the TGA’s assessment of safety and efficacy across the TRANSFORM and SUSTAIN program.

Evidence context

Long-term safety and efficacy data are drawn from the SUSTAIN-2 and SUSTAIN-3 open-label extension studies. These studies support a broadly consistent safety profile with extended use. Referring clinicians should note that data beyond 12 months of continuous use remains limited.
Submit Referral
0468 054 264
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Ready to refer a patient?

Referrals reviewed within 24–48 hours. Patients typically commence treatment within two weeks.

Submit a Referral
View Referral Process

Urgent query? Call 0468 054 264 

info@goodmindteam.com.au .

Work with Us

Summary of the pivotal TRANSFORM and SUSTAIN trial programs, real-world evidence, and MADRS outcome data for clinical reference.

Refer a patient:

Submit Referral
Check Patient Eligibility

Why join GoodMind?

Meaningful clinical work

Specialised TRD treatment — a growing, underserved field with strong evidence-based protocols and rapid clinical impact.

Veteran & first responder focus

Specialist clinical environment with experienced leadership in trauma and defence-related mental health.

National & growing

Expanding network across Australia with new clinic sites opening. Flexible sessional and full-time arrangements.Specialised TRD treatment — a growing, underserved field with strong evidence-based protocols and rapid clinical impact.

Current Openings

Psychiatric Nurse — Esketamine Administration

Multiple locations · Full-time & part-time · Darwin · Brisbane · Gold Coast · Sydney · Melbourne

Registered Nurse
Apply

Sessional Psychiatrist

Multiple locations · Sessional / VMO · AHPRA registration + Spravato training required

Sessional Psychiatrist
Apply

Clinical Coordinator

Multiple locations · Full-time · Patient liaison, scheduling, referral triage support

Clinical Coordinator
Apply

Nurse Practitioner

Sydney CBD & Melbourne · Full-time · NP registration required

Nurse Practitioner
Apply

Ready to refer a patient?

Referrals reviewed within 24–48 hours. Patients typically commence treatment within two weeks.

Submit a Referral
Check Eligibility First

Urgent query? Call 0468 054 264 

info@goodmindteam.com.au 

Clinic Carousel — GoodMind Therapeutics
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Dr David Graham

Medical Director and Psychiatrist

Dr Graham is passionate about social justice, trauma, and veteran and first responder mental health. He came to medicine following a successful career in Defence, which included two deployments to Afghanistan. This experience drew him to Psychiatry as a specialty. Dr Graham has advanced qualifications in addition to his MBBS, including a Masters of Psychiatric Medicine and a Doctor of Philosophy.

Dr Jennifer Long

Psychiatrist Consultant

Dr Jennifer Long is an accomplished psychiatrist with subspecialty expertise in psychosomatic medicine, pain medicine, neuropsychiatry, and psychotherapies.

With over a decade of clinical experience across both public and private sectors, Dr Long brings a deeply integrative and trauma-informed approach to mental health care, supporting patients holistically across mind and body.

Her commitment to evidence-based, compassionate, and integrative care reflects the core of GoodMind’s mission, ensuring every individual receives thoughtful, person-centred support tailored to their unique needs.

Dr . Dao Guo

Registrar psychiatrist

Dr Guo is a Registrar psychiatrist and Fellow of the Royal Australian and New Zealand College of Psychiatrists (FRANZCP).He completed the majority of his specialist psychiatric training at Royal Prince Alfred Hospital, where he gained extensive experience across acute inpatient, community, and emergency psychiatric services, managing a broad range of complex mental health presentations.

Dr Guo has a strong clinical and academic interest in substance use disorders, with particular research focus on e-cigarette use and mental health outcomes in veteran populations.

Dr Guo completed his Doctor of Medicine at the University of Western Australia, after obtaining a Bachelor of Biomedicine from the University of Melbourne. He is fluent in English and Mandarin.

Nick Pincombe

Pharmasist and Advisor

Nick joined the Royal Australian Air Force in 2003 and then transferred to the Australian Army in 2005. Nick was allocated to the Royal Australian Infantry Corps, commencing his regimental time at the 2nd Battalion, Royal Australian Regiment. He posted to various units until deploying on Operation Slipper in 2013.
Nick completed his pharmacy degree through the University of New England. Nick currently lives in Samford Valley with his wife and sons, and works locally at the Samford Pharmacy. Nicks interests include hiking, outdoor activities, nutrition, and veteran and mental health.

Amanda Neal

Partnerships Manager

As the wife of a former serving member who dedicated 15 years to the Defence Force, Amanda experienced firsthand the toll military life can take – not just on those who serve, but on the families who stand beside them. Over the years, she watched husband navigate the mental and physical challenges that come with service, and experienced the ripple effects that reach far beyond the uniform.
Amandaʼs mission is clear: to be a voice to ensure that every veteran, first responder, and their loved ones know they have options when it comes to their mental health.

Jodie Woolf

Clinical Care Lead & Health Consultant

Originally from South Africa, Jodie is a dedicated registered nurse, nurse immuniser, health consultant, and qualified naturopathic nutritionist with extensive experience across diverse healthcare settings, including mental health. She is also an Accredited Mental Health First Aider™ (MHFAider®) through MHFA Australia. Known for her warm, approachable nature and strong communication skills, Jodie is passionate about guiding individuals through their care journeys with empathy and professionalism. She focuses on comprehensive health assessments, coordination during treatment programs, and supporting individuals throughout their experience. Jodie brings a holistic perspective that integrates clinical knowledge with lifestyle and wellbeing insights. She embodies GoodMind Therapeutics’ commitment to delivering supportive, person-centred care. Outside of work, Jodie enjoys keeping up with the latest in health and wellness.

Dr. Lauren Barker

CEO & Co-Founder

Lauren began her career as a medical doctor in New Zealand, working for several years across a range of mental health and emergency medicine settings. She transitioned into management consulting with Bain & Company in Australia, to focus on system-level impact and has since worked with leading Australian healthcare organisations to improve access, efficiency, and outcomes for patients. At GoodMind, she brings together clinical and strategic expertise to help build a more compassionate, effective system for people seeking progressive mental health care.

Gaius Tan

COO & Co-Founder

Gaius combines his background as a pharmacist with extensive experience building and scaling digital and in-person healthcare models.

Before GoodMind, he led operational strategy and service delivery at Chemist Warehouse, Eucalyptus, and Mosh, developing national telehealth networks and multisite clinical operations.

He blends clinical insight with operational and commercial expertise to design safe, scalable, and patient-centred mental-health programs.

Thillak Naidu

Operations Associate

Thillak’s extensive experience across clinical research, pharmacology, and healthcare operations, Thillak brings a unique dual perspective to GoodMind Therapeutics. His career has spanned roles as a Clinical Research Coordinator and Clinical Trials Pharmacist with Te Whatu Ora | Te Toka Tumai Auckland, where he contributed to advancing innovative treatment approaches and ensuring adherence to rigorous clinical standards.

Operation Manager

Operation Manager

Jacqui brings more than 20 years’ experience in the healthcare sector, traversing the medical, allied health and wellness spheres. Prior to GoodMind, she held roles in operations management, clinic management, dispensary management, regulatory affairs, product development, and team leadership. During her time at Blackmores, she provided regulatory expertise on global projects, bringing herbal and nutritional supplements to market. This taught her valuable skills in project management, risk assessment, and fostering relationships with stakeholders and cross-functional teams. Jacqui has a particular interest in mental health and brain health, stemming from her training as a clinical naturopath. In addition to her naturopathy degree, she has completed a Certificate in Genomic and Precision Medicine, and more recently has undertaken studies towards a MScMed in pharmaceutical development. At GoodMind, she is tasked with the smooth and efficient running of day-to-day business operations. This includes daily activities across all clinics, where she combines operational expertise with clinical understanding and compassion.

Anne Louise

Clinic Lead in Darwin

Anne leads the Darwin clinical team with a calm, compassionate presence and a deep commitment to patient care. With extensive experience in mental health and wellbeing, she plays a key role in guiding individuals through their treatment journey — from initial assessment to ongoing support. Her leadership style is grounded in empathy and collaboration, ensuring that every person receives care that is tailored to their needs and delivered with the highest level of clinical excellence. Anne is passionate about creating a safe, supportive environment where individuals feel heard, understood, and empowered throughout their experience. Combining clinical expertise with a holistic understanding of health and lifestyle, Anne reflects GoodMind Therapeutics’ mission to deliver thoughtful, person-centred care. Beyond the clinic, she enjoys exploring new developments in the health and wellness space.
Find Support

As per the guidelines set by the Therapeutic Goods Administration (TGA), we cannot advertise prescription medications to the public. However, we are committed to providing the best possible care to our clients and offer a range of next-step therapies that can be discussed during a consultation with our team.